The Effectiveness of a Brief Mind-Body Intervention for Treating Depression in Community Health Center Patients



The objective of this pilot study was to examine the effects of a brief, 6-week, 1.5-hour mind-body intervention for depression (MBID) in patients being treated for depression in 2 community health centers.


The MBID taught techniques such as meditation that elicit the relaxation response (RR) in combination with additional resiliency-enhancing components. Clinical outcomes of 24 depressed patients were measured pre-MBID, at completion of MBID, and 3 months post-MBID, using the Center for Epidemiological Studies Depression Scale (CES-D 10), Quality of Life Scale (QoL5), SF-12 Health Survey (SF-12), and Health-Promoting Lifestyle Profile-II (HPLP-II).


Significant post-treatment improvements were shown in depressive symptoms, spiritual growth, mental health, and quality of life, with a median CES-D 10 change from 17.5 (interquartile ratio [IQR] 13.3–22) to 12 (IQR 10–17.5; P<.001); a median HPLP-II Spiritual Growth subscale change from 2.0 (IQR 1.8–2.3) to 2.3 (IQR 2.0–3.0; P=.002) and a median HPLP-II Stress Management sub-scale change from 2.0 (IQR 1.8–2.4) to 2.4 (IQR 2.0–2.9; P=.027); significant improvement in median score on the QoL-5 from 53.3 (IQR 47.5–62.5) at baseline to 63.3 at endpoint (IQR 50–70; P=.008). Three-month follow-up data suggest that the improvement in outcomes were sustained 3 months after the intervention.


Participation in a 6-week RR-based MBID is associated with an improvement in depression, spiritual growth, and mental health among depressed community health center patients.

Keywords: Mind-body, relaxation response, depression, community health centers



el objetivo de este estudio piloto era examinar los efectos de una intervención de cuerpo y mente breve para tratar la depre-sión (Mind-Body Intervention for Depression, MBID) de 6 semanas en sesiones de 1 hora y media de duración en pacientes tratados por depresión en dos centros de salud comunitarios.


las técnicas MBID enseñadas, como la meditación, que suscitan la respuesta de relajación (RR), en combinación con componentes adicionales de aumento de la resiliencia. Se midieron los resultados clínicos de 24 pacientes deprimidos antes de la MBID, una vez completada la MBID y 3 meses después de la MBID, utilizando la escala de depresión del Centro para estudios epidemiológicos (Center for Epidemiological Studies Depression Scale, CES-D 10), la escala de calidad de vida (CDV5), la encuesta de salud SF-12 (SF-12) y el perfil II de estilo vital de promo-ción de salud (Health-Promoting Lifestyle Profile II, HPLP-II).


se demostraron mejoras postratamiento significativas en los síntomas depresivos, crecimiento espiritual, salud mental y calidad de vida, con un cambio medio en el CES-D 10 de 17,5 (razón intercuartil [interquartile ratio, IQR] 13,3–22) a 12 (IQR 10–17,5; p<0,001); un cambio medio en la subescala HPLP-II de crecimiento espiritual de 2,0 (IQR 1,8–2,3) a 2,3 (IQR 2,0–3,0; p=0,002) y un cambio medio en la subescala HPLP-II de gestión del estrés de 2,0 (IQR 1,8–2,4) a 2,4 (IQR 2,0–2,9; p=0,027); mejora significativa en la puntuación media en la CdV-5 desde un valor inicial de 53,3 (IQR 47,5–62,5) a 63,3 en el momen-to de la valoración (IQR 50–70; p=0,008). Los datos del seguimiento de tres meses sugieren que la mejora de los resultados se mantuvo 3 meses después de la intervención.


la participación en una MBID de 6 semanas basada en RR se asocia con una mejora en la depresión, el crecimiento espiritual y la salud mental entre los pacientes deprimidos de centros de salud comunitarios.


1. Wells KB, Stewart A, Hays RD.
The functioning and well-being of depressed patients. Results from the medical outcomes study.
1989; 262(7): 914–9. [PubMed] []
2. Simon GE, Manning WG, Katzelnick DJ, Pearson SD, Henk HJ, Helstad CS.
Cost-effectiveness of systematic depression treatment for high utilizers of general medical care.
Arch Gen Psychiatry.
2001; 58(2): 181–7. [PubMed] []
3. Katon WJ.
Clinical and health services relationships between major depression, depressive symptoms, and general medical illness.
Biol Psychiatry.
2003; 54(3): 216–26. [PubMed] []
4. Katon W.
Depression and diabetes: unhealthy bedfellows.
Depress Anxiety.
2010; 27(4): 323–6. [PMC free article] [PubMed] []
5. Simon GE, Khandker RK, Ichikawa L, Operskalski BH.
Recovery from depression predicts lower health services costs.
J Clin Psychiatry.
2006; 67(8): 1226–31. [PubMed] []
6. US Department of Health and Human Services; Health Resources and Services Administration.
Primary Care: The Health Center Program.
Demographic trends
2009; patients by poverty status. Accessed February 16, 2015. []
7. Gresenz CR, Sturm R, Tang L.
Income and mental health: unraveling community and individual level relationships.
J Ment Health Policy Econ.
January;4(4):197–203. [PubMed] []
8. Silverman ME, Muennig P, Liu X, Rosen Z, Goldstein MA.
The impact of socioeconomic status on the neural substrates associated with pleasure.
Open Neuroimag J.
Aug 18; 3: 58–63. [PMC free article] [PubMed] []
9. Huurre T, Eerola M, Rahkonen O, Aro H.
Does social support affect the relationship between socioeconomic status and depression? A longitudinal study from adolescence to adulthood.
J Affect Disord.
2007;100(1-3):55–64. [PubMed] []
10. Park ER, Traeger L, Vranceanu AM, et al.
The development of a patient-centered program based on the relaxation response: the Relaxation Response Resiliency Program (3RP).
2013; 54(2): 165–74. [PubMed] []
11. Lewinsohn PM, Seeley JR, Roberts RE, Allen NB.
Center for Epidemiological Studies-Depression Scale (CES-D) as a screening instrument for depression among community-residing older adults.
Psychol Aging.
1997; 12(2): 277–87. [PubMed] []
12. Ware JE, Kosinski M, Turner-Bowker DM, et al.
SF-12v2. How to score version 2 of the SF-12 health survey (with a supplement documenting version 1).
Boston, MA: QualityMetric Inc; 2002. []
13. Gandek B, Ware JE, Aaronson NK, et al.
Cross-validation of item selection and scoring for the SF-12 Health Survey in nine countries: results from the IQOLA Project.
J Clin Epidemiol.
1998; 51(11): 1171–8. [PubMed] []
14. Pender NJ, Pender AR.
Attitudes, subjective norms, and intentions to engage in health behaviors.
Nurs Res.
1986; 35(1): 15–8. [PubMed] []
15. Carlson ED.
A case study in translation methodology using the Health-Promotion Lifestyle Profile II.
Public Health Nurs.
2000; 17(1): 61–70. [PubMed] []
16. Lindholt JS, Ventegodt S, Henneberg EW.
Development and validation of QoL5 for clinical databases. A short, global and generic questionnaire based on an integrated theory of the quality of life.
Eur J Surg.
2002; 168(2): 107–13. [PubMed] []
17. Wilcoxon F.
Individual comparisons by ranking methods.
1945; 1: 80–83. []
18. Jacquart J, Miller KM, Radossi A, et al.
The effectiveness of a community-based, mind-body group for symptoms of depression and anxiety.
Adv Mind Body Med.
2014; 28(3): 6–13. [PubMed] []
19. Alegria M, Canino G, Rios R, et al.
Inequalities in use of specialty mental health services among Latinos, African Americans, and non-Latin whites.
Psychiatr Serv.
2002; 53(12): 1547–55. [PubMed] []
20. Han E, Liu GG.
Racial disparities in prescription drug use for mental illness among population in US.
J Ment Health Policy Econ.
2005; 8(3): 131–43. [PubMed] []
21. Harman JS, Edlund MJ, Fortney JC.
Disparities in the adequacy of depression treatment in the United States.
Psychiatr Serv.
2004; 55(12): 1379–85. [PubMed] []
22. Jouper J, Hassmen P.
Exercise intention, age and stress predict increased qigong exercise adherence.
J Bodyw Mov Ther.
2009; 13(2): 205–11. [PubMed] []
23. Le HN, Perry DF, Stuart EA.
(2011). Randomized controlled trial of a preventive intervention for perinatal depression in high-risk Latinas.
J Consult Clin Psychol.
2011; 79(2): 135–41. [PubMed] []
24. Piette JD, Richardson C, Himle J, et al.
A randomized trial of telephonic counseling plus walking for depressed diabetes patients.
Med Care.
2011; 49(7): 641–8. [PMC free article] [PubMed] []
25. Boye B, Lundin KE, Jantschek G, et al.
INSPIRE study: Does stress management improve the course of inflammatory bowel disease and disease-specific quality of life in distressed patients with ulcerative colitis or Crohn’s disease? A randomized controlled trial.
Inflamm Bowel Dis.
2011; 17(9): 1863–73. [PubMed] []
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